H335 · Hazard statementMay cause respiratory irritation

Hazard statementHealth

H335 is the GHS hazard statement “May cause respiratory irritation”. It is used for Specific target organ toxicity, single exposure; Respiratory tract irritation (chapter 3.8), Category 3. The English wording is the same as UN GHS Rev.11 in US OSHA, EU CLP and Canada. Canada’s official French text is “Peut irriter les voies respiratoires” and Mexico’s Spanish text is “Puede irritar las vías respiratorias”. The UN GHS Rev.11 label matrix lists 7 precautionary statements for it (UN only).

Maintained by Valenc. Data checked 2026-10-20.

Heading text: UN GHS Rev.11 Annex 3. Wording can differ by jurisdiction; see the table below.

Wording by jurisdiction

UN GHS Rev.11

Same as UN

GHS Rev.11 (2025), Annex 3

May cause respiratory irritation

UN GHS Rev.11, Annex 3, Table A3.1.2, PDF p. 304

US OSHA HCS

Same as UN

HCS 2024 · primarily GHS Rev.7, some Rev.8

May cause respiratory irritation

29 CFR 1910.1200 App. C, matched by wording

EU CLP

Same as UN

EU_CLP_2025 · consolidated 1 Jul 2026

May cause respiratory irritation.

EU CLP (Reg. (EC) No 1272/2008), Annex III, Part 1

Canada (EN)

Same as UN

WHMIS_2022 · GHS Rev.7 (Rev.8 for chemicals under pressure)

May cause respiratory irritation

GHS Rev.7 Annex 3 Table A3.1

Canada (FR)

Adopted

WHMIS_2022 · SGH Rév.7, texte officiel

Peut irriter les voies respiratoires

GHS Rev.7 Annex 3 Table A3.1

Mexico (ES)

Adopted

NOM-018-STPS-2015 · GHS 5th revised edition

Puede irritar las vías respiratorias

Toxicidad específica de órganos blanco (exposición única); irritación de las vías respiratorias · 3

NOM-018-STPS-2015, DOF 9 October 2015, Apéndice C, Tabla C.2, PDF p. 32

Hazard classes and categories

Specific target organ toxicity, single exposure; Respiratory tract irritation (chapter 3.8) · Category 3

UN GHS Rev.11 Annex 3, sections 1 and 2

FRToxicité pour certains organes cibles, exposition unique; Irritation des voies respiratoires (chapitre 3.8); · catégorie 3

ESToxicidad específica de órganos blanco (exposición única); irritación de las vías respiratorias · 3 (NOM-018-STPS-2015)

Pictogram: Exclamation mark (GHS07)

UN GHS Rev.11 Annex 3, section 3. Pictogram rules can differ by jurisdiction; see the GHS pictogram guide.

P statements in the UN GHS Rev.11 label matrix only

UN GHS Rev.11 only. EU CLP, US OSHA, Canada (GHS Rev.7) and Mexico assign different P statements; check the regulation for your market.

Specific target organ toxicity (single exposure) (chapter 3.8), categories 3 (PDF p. 401)
P261 P271 P319 P405 P501 P304+P340 P403+P233

UN GHS Rev.11 Annex 3, section 3. Each table covers the categories named; a P statement may apply to only some of them. Many apply only under conditions; check the conditions for use before putting them on a label.

Related codes

H336 H370 H371

Change in UN GHS Rev.11

No change to the wording or the hazard classes in Annex 3 compared with Rev.10.

Sources

Each cell in the table names the official table and page for H335. Full citations, links and revision notes for UN GHS Rev.11, US OSHA, EU CLP, Canada and Mexico: Sources and revision notes.

These are regulatory phrases for labels and safety data sheets. Check them against the official source for your jurisdiction before use.