H373 · Hazard statementMay cause damage to organs (state all organs affected, if known) through prolonged or repeated exposure (state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard)
H373 is the GHS hazard statement “May cause damage to organs (state all organs affected, if known) through prolonged or repeated exposure (state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard)”. It is used for Specific target organ toxicity, repeated exposure (chapter 3.9), Category 2. The English wording is the same as UN GHS Rev.11 in US OSHA and Canada. The wording differs in EU CLP. The Canadian French and Mexican Spanish wording is in the table below. The UN GHS Rev.11 label matrix lists 3 precautionary statements for it (UN only).
Heading text: UN GHS Rev.11 Annex 3. Wording can differ by jurisdiction; see the table below.
Wording by jurisdiction
UN GHS Rev.11
Same as UNMay cause damage to organs (state all organs affected, if known) through prolonged or repeated exposure (state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard)
UN GHS Rev.11, Annex 3, Table A3.1.2, PDF p. 305
US OSHA HCS
Same as UNMay cause damage to organs <…> through prolonged or repeated exposure <<…>>
29 CFR 1910.1200 App. C, matched by wording
EU CLP
DiffersMay cause damage to organs <or state all organs affected, if known> through prolonged or repeated exposure <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>.
EU CLP (Reg. (EC) No 1272/2008), Annex III, Part 1
Canada (EN)
Same as UNMay cause damage to organs ( state all organs affected, if known) through prolonged or repeated exposure (state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard)
GHS Rev.7 Annex 3 Table A3.1
Canada (FR)
AdoptedRisque présumé d’effets graves pour les organes (indiquer tous les organes affectés, s’ils sont connus) à la suite d’expositions répétées ou d’une exposition prolongée (indiquer la voie d’exposition s’il est formellement prouvé qu’aucune autre voie d’exposition ne conduit au même danger)
GHS Rev.7 Annex 3 Table A3.1
Mexico (ES)
AdoptedPuede provocar daños en los órganos (indíquense todos los órganos afectados, si se conocen) tras exposiciones prolongadas o repetidas (indíquese la vía de exposición si se ha demostrado concluyentemente que ninguna otra vía es peligrosa)
Toxicidad específica de órganos blanco (exposiciones repetidas) · 2
NOM-018-STPS-2015, DOF 9 October 2015, Apéndice C, Tabla C.2, PDF p. 33
Hazard classes and categories
- Specific target organ toxicity, repeated exposure (chapter 3.9) · Category 2
UN GHS Rev.11 Annex 3, sections 1 and 2
FRToxicité pour certains organes cibles, expositions répétées (chapitre 3.9) · catégorie 2
ESToxicidad específica de órganos blanco (exposiciones repetidas) · 2 (NOM-018-STPS-2015)
Pictogram: Health hazard (GHS08)
UN GHS Rev.11 Annex 3, section 3. Pictogram rules can differ by jurisdiction; see the GHS pictogram guide.
Change in UN GHS Rev.11
No change to the wording or the hazard classes in Annex 3 compared with Rev.10.
Notes
EU CLP wording differs from UN GHS Rev.11.
Sources
Each cell in the table names the official table and page for H373. Full citations, links and revision notes for UN GHS Rev.11, US OSHA, EU CLP, Canada and Mexico: Sources and revision notes.
These are regulatory phrases for labels and safety data sheets. Check them against the official source for your jurisdiction before use.