H401 · Hazard statementToxic to aquatic life

Hazard statementEnvironmentalNot adopted: US, EU, Canada, Mexico

H401 is the GHS hazard statement “Toxic to aquatic life”. It is used for Hazardous to the aquatic environment, acute hazard (chapter 4.1), Category 2. Not adopted in US OSHA, EU CLP, Canada and Mexico. The UN GHS Rev.11 label matrix lists 2 precautionary statements for it (UN only).

Maintained by Valenc. Data checked 2026-10-20.

Heading text: UN GHS Rev.11 Annex 3. Wording can differ by jurisdiction; see the table below.

Wording by jurisdiction

UN GHS Rev.11

Same as UN

GHS Rev.11 (2025), Annex 3

Toxic to aquatic life

UN GHS Rev.11, Annex 3, Table A3.1.3, PDF p. 307

US OSHA HCS

Not adopted

HCS 2024 · primarily GHS Rev.7, some Rev.8

No matching OSHA hazard class or category (not adopted by OSHA).

EU CLP

Not adopted

EU_CLP_2025 · consolidated 1 Jul 2026

Not listed in EU CLP Annex III or IV.

Canada (EN)

Not adopted

WHMIS_2022 · GHS Rev.7 (Rev.8 for chemicals under pressure)

Environmental hazard classes are not adopted in the HPR.

Canada (FR)

Not adopted

WHMIS_2022 · SGH Rév.7, texte officiel

Environmental hazard classes are not adopted in the HPR.

Mexico (ES)

Not adopted

NOM-018-STPS-2015 · GHS 5th revised edition

NOM-018-STPS-2015 covers physical and health hazards only (no environmental hazard statements).

Hazard classes and categories

Hazardous to the aquatic environment, acute hazard (chapter 4.1) · Category 2

UN GHS Rev.11 Annex 3, sections 1 and 2

P statements in the UN GHS Rev.11 label matrix only

UN GHS Rev.11 only. EU CLP, US OSHA, Canada (GHS Rev.7) and Mexico assign different P statements; check the regulation for your market.

Hazardous to the aquatic environment, short-term (acute) hazard (chapter 4.1), categories 2, 3 (PDF p. 406)
P273 P501

UN GHS Rev.11 Annex 3, section 3. Each table covers the categories named; a P statement may apply to only some of them. Many apply only under conditions; check the conditions for use before putting them on a label.

Related codes

H400 H402

Change in UN GHS Rev.11

No change to the wording or the hazard classes in Annex 3 compared with Rev.10.

Sources

Each cell in the table names the official table and page for H401. Full citations, links and revision notes for UN GHS Rev.11, US OSHA, EU CLP, Canada and Mexico: Sources and revision notes.

These are regulatory phrases for labels and safety data sheets. Check them against the official source for your jurisdiction before use.